Game crashes to Desktop a few seconds after entering Holten (and Grimhaven)

I leveled up another char and yesterday as i entered Holten in the Interludes and i crashed.
Today i tried again and the same happened. When i reload the game, it crashes again.

I'm playing an ED/C Lich.

I did not had this on my first playthrough through the campain with LA Deadeye and i'm a bit worried i Will have troubles beating the campaign over this.

During 0.3 i also had the same trouble with a couple maps, one of them is Grimhaven. I could not run Grimhaven maps during all of 0.3

I could fix most random crashes i had throughout 0.3 by switching to Vulcan, but it doesn't solve Holten or Grimhaven. I also briefly tried to change back to DirextX12 in Holten, but this also crashes to Desktop.

I don't think it's my PC. It's a 12th Gen i7, a 4047ti, 32gb (fast) DDR4 and a Samsung 980 SSD.

I hope with will be fixed for 0.4. Currently i can't play he game any further.